Objeto virtual de aprendizaje para fortalecer habilidades investigativas en auxiliares de enfermería en el contexto de las enfermedades neurodegenerativas.

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dc.contributor.advisorRodríguez Cepeda, Rodrigospa
dc.contributor.authorIbáñez Martínez, Angélica Tatianaspa
dc.contributor.authorRomán Poveda, Luz Ángelaspa
dc.coverage.spatialBogotá, Colombia
dc.coverage.temporal2013-2026
dc.date.accessioned2026-07-23T14:09:08Z
dc.date.available2026-07-23T14:09:08Z
dc.date.issued2026
dc.description.abstractEsta investigación fortalece las habilidades investigativas (pensamiento crítico e interpretación) en auxiliares de enfermería mediante un Objeto Virtual de Aprendizaje (OVA) llamado SynCurm, en el contexto de la enfermedad de Parkinson. Se emplea un estudio de casos múltiples con enfoque mixto exploratorio-descriptivo (n=5). Se extrae y caracteriza curcumina de Curcuma longa con solventes eutécticos naturales (NADES), validando el extracto mediante marcha fitoquímica, IR, HPLC y docking molecular. Los resultados cuantitativos muestran una mejora en la muestra estudiada (p=0,042; media de entrada=29,6/40, media de salida=33,8/40). El análisis cualitativo con Atlas.ti confirma tendencias favorables, destacando el avance de una participante con más de cinco años de experiencia (+10 puntos). Como productos derivados se generan el OVA, un kit didáctico portátil, un cuestionario adaptado del PENCRISAL y un alimento funcional. El estudio concluye que el OVA SynCurm tiene un alto potencial didáctico para nivelar conocimientos en grupos heterogéneos y fortalecer el pensamiento crítico, sentando bases para futuras investigaciones.spa
dc.description.abstractenglishThis study enhances the research skills (critical thinking and interpretation) of nursing assistants through a Virtual Learning Object (VLO) called SynCurm, in the context of Parkinson’s disease. A multiple-case study with a mixed exploratory-descriptive approach (n=5) is employed. Curcumin is extracted and characterized from Curcuma longa using natural eutectic solvents (NADES), and the extract is validated through phytochemical profiling, IR, HPLC, and molecular docking. The quantitative results show an improvement in the study sample (p=0.042; baseline mean=29.6/40, post-intervention mean=33.8/40). Qualitative analysis using Atlas.ti confirms favorable trends, highlighting the progress of one participant with more than five years of experience (+10 points). Derivative products include the OVA, a portable educational kit, a questionnaire adapted from PENCRISAL, and a functional food. The study concludes that the SynCurm OVA has high educational potential for leveling knowledge in heterogeneous groups and strengthening critical thinking, laying the groundwork for future research.eng
dc.description.degreelevelPregradospa
dc.description.degreenameLicenciado en Químicaspa
dc.description.researchareaAlimentomica y enseñanza de las ciencias
dc.format.mimetypeapplication/pdfspa
dc.identifier.instnameinstname:Universidad Pedagógica Nacionalspa
dc.identifier.reponamereponame: Repositorio Institucional UPNspa
dc.identifier.repourlrepourl: http://repositorio.pedagogica.edu.co/
dc.identifier.urihttp://hdl.handle.net/20.500.12209/22589
dc.language.isoes
dc.publisherUniversidad Pedagógica Nacionalspa
dc.publisher.facultyFacultad de Ciencia y Tecnologíaspa
dc.publisher.programLicenciatura en Químicaspa
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dc.relation.referencesWiley, D. A. (2000). Connecting learning objects to instructional design theory. http://opencontent.org/docs/lo_do.pdf
dc.relation.referencesZhang, X., Li, Y., Xu, H., & Zhang, Y. W. (2014). The γ-secretase complex: from structure to function. Frontiers in cellular neuroscience, 8, 427. https://doi.org/10.3389/fncel.2014.00427
dc.rights.accessrightsinfo:eu-repo/semantics/openAccess
dc.rights.accessrightshttp://purl.org/coar/access_right/c_abf2
dc.rights.creativecommonsAttribution-NonCommercial-NoDerivatives 4.0 International
dc.source.urihttps://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subjectObjeto Virtual de Aprendizaje (OVA)spa
dc.subjectPedagogía clínicaspa
dc.subjectHabilidades investigativasspa
dc.subjectEnfermedad de Parkinsonspa
dc.subjectAlfa-sinucleinaspa
dc.subjectCurcuminaspa
dc.subjectSolvente Eutéctico Profundo Narutal (NADE)spa
dc.subjectB-learningspa
dc.subject.keywordsVirtual Learning Object (VLO)eng
dc.subject.keywordsClinical pedagogyeng
dc.subject.keywordsResearch skillseng
dc.subject.keywordsParkinson's diseaseeng
dc.subject.keywordsAlpha-synucleineng
dc.subject.keywordsCurcumineng
dc.subject.keywordsNatural Deep Eutectic Solvent (NADES)eng
dc.subject.keywordsB-learningeng
dc.titleObjeto virtual de aprendizaje para fortalecer habilidades investigativas en auxiliares de enfermería en el contexto de las enfermedades neurodegenerativas.spa
dc.title.translatedVirtual learning object to strengthen research skills among nursing assistants in the context of neurodegenerative diseases.eng
dc.typeinfo:eu-repo/semantics/bachelorThesisspa
dc.type.coarhttp://purl.org/coar/resource_type/c_7a1feng
dc.type.driverinfo:eu-repo/semantics/bachelorThesiseng
dc.type.hasVersioninfo:eu-repo/semantics/acceptedVersion
dc.type.localTesis/Trabajo de grado - Monografía - Pregradospa

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